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Cholinergic neuron : ウィキペディア英語版 | Cholinergic neuron A cholinergic neuron is a nerve cell which mainly uses the neurotransmitter acetylcholine (ACh) to send its messages. Many neurological systems are cholinergic. Cholinergic neurons provide the primary source of acetylcholine to the cerebral cortex, and promote cortical activation during both wakefulness and rapid eye movement sleep. In recent years, the cholinergic system of neurons has been a main focus of research in aging and neural degradation, specifically as it relates to Alzheimer's Disease. The dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections are among the earliest pathological events in Alzheimer's Disease. == Anatomy== Most research involving cholinergic neurons involves the basal forebrain cholinergic neurons. However, cholinergic neurons only represent about 5% of the total basal forebrain cell population.〔 Most of these neurons originate in different areas of the basal forebrain and have extensive dendritic fields that project into almost all layers of the cortex.〔〔 Basal forebrain cholinergic neurons are homologous within a particular basal forebrain region but vary across different regions.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Cholinergic neuron」の詳細全文を読む
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